ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Preparation, Characterization, and Antimicrobial Activity of Some 5-Alkyl-2,4,6-substituted Pyrimidines

M. Koóš and Z. Novotná

Institute of Chemistry, Slovak Academy of Sciences, SK-842 38 Bratislava

Abstract: Fifteen new 5-alkyl-2,4,6-substituted pyrimidines were prepared by the cyclization reactions from corresponding alkylmalononitriles, ethyl 2-cyanoalkanoates or 2-alkyl-3-oxobutyrates where alkyl represented hexyl, heptyl or octyl. Spectral data as well as values of minimum inhibitory concentration against selected microorganisms are given. No significant antimicrobial efficiency was found in this respect.

Full paper in Portable Document Format: 484a278.pdf

Chemical Papers 48 (4) 278–281 (1994)