ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Solar light-mediated graphene surface functionalization through diazo-chemistry route for regioselective Sp³C–H bond activation and 1,4-NADH regeneration for enhanced catalytic efficiency

Surendra K. Jaiswal, Rajesh K. Yadav, Dinesh K. Mishra, Shaifali Mishra, Rehana Shahin, Kanchan Sharma, Arun K. Dubey, Navneet K. Gupta, D. K. Dwivedi, and Jin Ook Baeg

Department of Chemistry and Environmental Science, Madan Mohan Malaviya University of Technology, Gorakhpur, India

E-mail: rajeshkr_yadav2003@yahoo.co.in

Received: 28 March 2025  Accepted: 30 June 2025

Abstract:

By employing graphene-2,4,6-tribromoaniline for the regioselective activation of sp³ C–H bonds, the study explores a new catalytic mechanism that facilitates the fixation of NAD⁺ to 1,4-NADH in aqueous media under solar light circumstances. The technique provides a sustainable mechanism for organic transformations by demonstrating the effective manipulation of C–H bonds. In this photoinduced reaction, graphene combined with tribromoaniline acts as a strong catalyst, guaranteeing great selectivity and few byproducts. Biochemical activities depend on the activation of NAD⁺ to 1,4-NADH, and this photocatalytic method offers a more environmentally friendly option than conventional techniques. The promise for creating sustainable, environmentally friendly solutions for intricate organic reactionsespecially in bioorganic chemistry, with uses in energy storage and enzymatic processes, is demonstrated by the combination of solar energy and sophisticated catalysis. This discovery presents intriguing opportunities for further study in biocatalysis and green chemistry.

Keywords: Graphene; Graphene-2,4,6-Tribromoaniline photocatalyst; 1,4-NADH regeneration; Sp3 C–H bonds formation; Solar energy

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-025-04287-y

Chemical Papers 79 (11) 7787–7798 (2025)