Received: 9 September 2020 Accepted: 6 February 2021
Abstract:
Abstract
A simple and efficient synthesis of aryl-himachalene benzylamines derivatives from himachalenes, natural sesquiterpenes isolated from essential oil of Cedrus atlantica, via chloromethylation reaction. Various aromatic amines were used to provide the corresponding secondary benzylamines in good yields. The reaction offers a first practical synthetic method for the preparation of a range of sesquiterpenes with benzylamines moiety.