ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Study on the biosynthesis and antibacterial effect of Zinc Oxide Nanoparticles using aloe vera latex extract

Khadija Khaldoune, Meriem Rafya, Issam Louchachha, Ali Hasnaoui, Fatiha Benkhalti, Naima Fdil, and Mustapha Ait Ali

Faculté Des Sciences Semlalia, Laboratoire de Chimie Moléculaire, Université Cadi Ayyad, Marrakech, Morocco

E-mail: k.khaldoune.ced@uca.ac.ma

Received: 9 December 2024  Accepted: 13 May 2025

Abstract:

In this study, we explore an effective method for the synthesis of ZnO nanoparticles through an environmentally friendly process using Aloe vera latex extract at three different temperatures: room temperature, 50°C, and 100°C. The successful synthesis of ZnO Nanoparticles has been confirmed by different spectroscopic analyses such as XRD that showed the pure phase of ZnO with hexagonal shape, UV–Vis showed the absorption band of ZnO at 360 nm, and FT-IR and SEM–EDX showed the nanostructure size of the synthesized nanoparticles. This method allowed the obtention of nanoparticles with the size of 20.65 ± 9.86, 19.89 ± 3.76, and 21.37 ± 5.43 nm for ZnO_RT, ZnO_50°C, and ZnO_100°C respectively. The antibacterial activity of the three synthesized nanoparticles was evaluated against four bacteria: E. coli, P. aeruginosa, S. aureus, and E. faecalis. Notably, the nanoparticles synthesized at 50 °C have demonstrated the highest activity with MIC of 0.16, 0.63, 0.08, and 0.08 mg/mL against E. coli, P. aeruginosa, S. aureus, and E. faecalis, respectively.

Keywords: Bionanoelectronics; Metal Oxides; Nanomaterial; Nanomedicine and Nanotoxicology; Nanoparticle Synthesis; Nanoparticles; Green synthesis; ZnO Nps; Aloe vera latex; Biosynthesis; Antibacterial effect

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-025-04133-1

Chemical Papers 79 (8) 5399–5407 (2025)