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Recent developments in synthesis of embelin heterocyclic derivatives and their biological applications

Satish Gudala, Archi Sharma, V. Rajeswer Rao, Awanish Kumar, and Santhosh Penta

National Institute of Technology, Raipur, India

 

E-mail: spenta.che@nitrr.ac.in

Abstract: Embelin (2,5-dihydroxy-3-undecyl-1,4-benzoquinone) has attracted a great deal of synthetic attention as a biologically active heterocyclic compound in the last decades. The high reactivity of its carbonyl groups, active methylene group, and hydroxyl groups represents challenges to many organic reactions for the synthesis of various embelin derivatives. This review summarizes for the first time the most recent and relevant approaches towards the synthesis of embelin-linked heterocyclic derivatives.

Keywords: Embelin heterocyclic derivatives ; Biological activities of embelin derivatives ; Rectivity of embelin ; Knoevenagel condensation ; Hetero-Diels Alder reaction 

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-017-0348-8

 

Chemical Papers 72 (5) 1065–1080 (2018)

Tuesday, June 28, 2022

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