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Synthesis of thiohydantoin and rhodanine derivatives from 4-substituted cinnamoyl isothiocyanates

M. Dzurilla and E. Demjánová

Department of Organic Chemistry, Faculty of Natural Sciences, P. J. Šafárik University, 041 67 Košice

 

Abstract:  Synthesis of 3-(4-substituted cinnamoyl)-2-thiohydantoins and 3-(4-substituted cinnamoyl)rhodanines bty cyclization of 4-substituted cinnamoyl isothiocyanates with glycine and thioglycolic acid, respectively in acid medium is described. The structures of the synthesized compounds are proved by infrared and ultraviolet spectra.

Full paper in Portable Document Format: 285a693.pdf

 

Chemical Papers 28 (5) 693–696 (1974)

Monday, June 27, 2022

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