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Synthesis and antimicrobial activity of 2-(alkylthio)-6-salicylideneaminobenzothiazoles

E. Sidóová and P. Foltínová

Institute of Chemistry, Komenský University, 816 50 Bratislava

 

Abstract: Sixteen 2-alkylthio-6-salicylideneaminobenzothiazoles have been prepared by the reaction of salicylaldehyde with 2-alkylthio-6-aminobenzothiazoles and their structures have been proved by 'H-n.m.r. spectroscopy. The synthesized compounds were tested for antimicrobial activity. The highest fungicidal and fungistatic activities were found with benzyl derivative in 12.5 and 3.1 μg/ml concentrations, respectively against Trichophyton rubrum.

Full paper in Portable Document Format: 342a278.pdf

 

Chemical Papers 34 (2) 278–282 (1980)

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