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ISSN electronic edition: 1336-9075
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2',5'-Diazachalcones. I. Preparation, structure, and antibacterial effects of some substituted 2',5'-diazachalcones

D. Dvořáčková, J. Zámocká, J. Heger, A. Nagy, and V. Hartelová

Department of Inorganic and Organic Chemistry, Faculty of Pharmacy, Komenský University, 880 34 Bratislava

 

Abstract:  Ten hitherto unknown 2;5'-diazachalcones variously substituted at the isocyclic residue have been prepared by means of a modified Claisen—Schmidt condensation of methylpyrazinyl ketone with aromatic aldehydes. The structure of the substances was verified by i.r. and 1H-n.m.r. spectral data. The substances show antibacterial effects towards Staphylococcus aureus, Bacillus subtilis, and Escherichia coli.

Full paper in Portable Document Format: 342a263.pdf

 

Chemical Papers 34 (2) 263–268 (1980)

Wednesday, February 19, 2020

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