ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
Modeling of enzymatic reaction in an airlift reactor using an axial dispersion model
Ivan Sikula and Jozef Markoš
Institute of Chemical and Environmental Engineering, Faculty of Chemical and Food Technology, Slovak University of Technology, SK-812 37 Bratislava, Czechoslovakia
Received: 19 April 2007 Revised: 14 June 2007 Accepted: 20 June 2007
Abstract: This work was focused on modeling of biochemical processes in a 40-L internal-loop airlift reactor. Due to different mixing
in the specific zones of the reactor four main sections, bottom, riser, separator and downcomer, were recognized. Each zone
was modeled by an adequate mixing model: bottom and separator sections by the model of ideally-stirred reactor; riser and
downcomer sections by the model of plug-flow reactor with axial dispersion. In the model, the effects of mass transfer, hydrodynamics,
and reaction kinetics were taken into account. The model of the reactor was experimentally verified by the aerobic enzymatic
oxidation of glucose to gluconic acid. Simulations are in good agreement with experimental data.
Keywords: airlift reactor - modeling - axial dispersion model - gluconic acid - glucose oxidase - catalase
Full paper is available at www.springerlink.com.
Chemical Papers 62 (1) 10–17 (2008)