ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
Benzothiazole compounds. 27. Alkylation and antifungal activity of some 2-R-3-(2-mercaptoethyl)benzothiazolines
S. Mikulášek, V. Sutoris, A. Perjéssy, and P. Foltínová
Department of Organic Chemistry, Faculty of Natural Sciences,
Komenský University, CS-842 15 Bratislava
Abstract: The series of 2-R-3-(2-R'-thioethyl)benzothiazolines and allyl esters of
bis[2-(2-R-3-benzothiazolinyl)ethylthio]acetic acid were synthesized by alkylation of 3-(2-mercaptoethyl)-2-benzothiazolinone oxime, 3-(2-mercaptoethyl)-2-benzothiazolinone semicarbazone, and 3-(2-mercaptoethyl)-2-benzothiazolinone thiosemicarbazone with corresponding reactive compounds.
The structures of prepared compounds were confirmed by infrared spectra.
The antibacterial activity of compounds is rather low, however the results of
the antifungal tests showed more favourable results.
Full paper in Portable Document Format: 406a779.pdf
Chemical Papers 40 (6) 779–790 (1986)
Wednesday, October 21, 2020