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A Convenient Synthesis of Polyfunctionally Substituted (Acridin-9-yl)imino-l,3-thiazolidin-4-ones and Spiro[9,10-dihydroacridine-9,4'-thiazolidines]

P. Kristian, I. Chomča, J. Bernát, and J. Imrich

Department of Organic Chemistry, Faculty of Natural Sciences, P. J. Šafárik University, SK-041 67 Košice

 

Abstract: 1-(Acridin-9-yl)-3-disubstituted thioureas react with methyl bromoacetate and bromoacetonitrile, respectively, depending on a substituent bulkiness, to polyfunctionally substituted (acridin-9-yl)imino-l, 3-thiazolidin-4-ones and spiro[9,10-dihydroacridine-9,4'-thiazolidines]. Reactions represent the simple and convenient way to synthesize the title compounds with possible antibacterial activity. Based on their spectral data, the structure of products is discussed.

Full paper in Portable Document Format: 531a49.pdf

 

Chemical Papers 53 (1) 49–52 (1999)

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