ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Novel synthetic methods toward the synthesis of Betti bases: an update

Aqsa Mushtaq, Ameer Fawad Zahoor, Sajjad Ahmad, Bushra Parveen, and Kulsoom Ghulam Ali

Department of Chemistry, Government College University Faisalabad, Faisalabad, Pakistan

E-mail: fawad.zahoor@gmail.com

Abstract:

Betti bases have gained significant importance in medicinal chemistry as they exhibit a wide range of pharmacological applications such as anti-tumor, anti-microbial, anti-fungal, anti-inflammatory and anti-tubercular activities. Moreover, they are of great synthetic utility owing to their usage as catalysts and as ligands in asymmetric synthesis. Due to their innumerable uses, various scientists have been continuously devising enormous methodologies, using a range of catalysts and modified reaction conditions for the synthesis of Betti bases. This review article focuses on efficient and novel facile synthetic protocols for their synthesis that have been utilized by various research groups since 2017.

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-023-02825-0

Chemical Papers 77 (9) 4751–4795 (2023)