ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
Catalytic activity of Schiff base monocrystal and its application for colorimetric detection of dopamine
Qinghua Weng, Shuyu Chen, Jinquan Yi, Siqi Huang, Jiaye Wang, Fei Wang, Xing Shang, Jie Kang, and Zhizhong Han
School of Pharmacy, Fujian Medical University, Fuzhou, People’s Republic of China
Received: 21 May 2020 Accepted: 27 September 2020
In this work, we used 2-amino-4-methylphenol and terephthalaldehyde as reactants to synthesize a new type of Schiff base crystal (MAPTPA). It is yellow with an empirical formula of C22H20N2O2. The synthesized MAPTPA exhibits an intrinsic visible light-induced oxidase-like catalytic activity without the use of destructive H2O2. The results show that dissolved oxygen plays an important role in the catalytic reaction process and 1O2 is the crucial reactive species responsible for TMB oxidation. The results of Michaelis–Menten kinetics demonstrate that MAPTPA has high substrate affinity and catalytic efficiency. Based on the catalytic activity of MAPTPA, we developed a sensitive visual sensing strategy for dopamine (DA) detection. A high linear relationship is observed in the range of 0.01–100 μM with a detection limit (LOD) of 6.70 nM. Therefore, the as-prepared Schiff base monocrystal may be used as an oxidase mimic for life sciences in the future, such as biosensor, biosynthesis, photodynamic therapy, etc.
Keywords: Schiff base; Oxidase mimic; Catalytic activity; Colorimetric detection; Dopamine
Full paper is available at www.springerlink.com.
Chemical Papers 75 (3) 1259–1266 (2021)